ProgestoMend™ is a combination of plant extracts, including chasteberry, specifically designed to help relieve premenstrual and menopausal symptoms.

ProgestoMend™, provided by Douglas Laboratories® is a Hormone Specific Formulation™ of phytoprogesterones, progestogenic adaptogens and functional mimetics of progesterone. This formulation is designed to promote optimal function of progesterone by maintaining the health of progesterone producing glands and by supporting the healthy function of progesterone responsive tissues.

Chasteberry extract (Vitex agnus-castus) contains active constituents that play a role in hormone activity, including dopaminergic compounds that suppress the release of prolactin. This herb also acts on the pituitary gland to stimulate the release of luteinizing hormone, which results in increased progesterone levels. By balancing prolactin and progesterone levels, two important hormones involved in the menstrual cycle, chasteberry helps to restore menstrual regularity. Decreasing prolactin levels can also help to relieve premenstrual symptoms, which commonly include mood, headache, bloating, and breast fullness.

By inhibiting prolactin synthesis, regulating the health of progesterone producing glands and mediating the function of progesterone responsive tissues, chasteberry also helps relieve symptoms associated with menopause, such as hot flushes as well as hormonally induced acne.

A study published in the Journal of Women’s Health & Gender-Based Medicine found that after being treated with vitex for three menstrual cycles, 93 percent of patients reported a decrease in the number of PMS symptoms or a complete end of PMS complaints.

Passion flower has been included in this formula as it can reduce menopausal symptoms such as vasomotor signs (hot flashes and night sweats), insomnia, depression, anger and headaches.

ProgestoMend™ contains additional herbs used in traditional Ayurvedic and Chinese medicine, including forskohlii, crampbark, Di huang and white peony.

The synergistic combination of specific herbs in ProgestoMend™ support important functions associated with optimal progesterone health:

• Supports the natural production of progesterone
• Support healthy adrenal function, a major site of progesterone production
• Promote progesterone response in target tissue through the use of herbs with progesterone receptor agonist activity.
• Promotes healthy function of bone, heart, brain, breasts, uterus & other progesterone sensitive tissues with progesterone mimetic herbs.
• Support healthy inflammation, antispasmodic and anxiolytic properties of progesterone with progesterone mimetic herbs.
• Supports healthy brain function, memory, and cognition, and enhances mood while promoting tranquility.

INDICATIONS

ProgestoMend™ may be a useful dietary supplement for individuals wishing to support healthy progesterone production and function.

Indications:

• Premenstrual symptoms
• Menstrual irregularity
• Menopausal symptoms

REFERENCES:

1. Loch EG. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus.  J Womens Health Gend Based Med. 2000 Apr;9(3):315-20. 
2. Rani A, Sharma A. The genus Vitex: A review. Pharmacogn Rev. 2013;7(14):188–198. doi:10.4103/0973-7847.120522
3. Fahami F, Asali Z, Aslani A, Fathizadeh N. A comparative study on the effects of Hypericum Perforatum and passion flower on the menopausal symptoms of women referring to Isfahan city health care centers. Iran J Nurs Midwifery Res. 2010;15(4):202–207.
4. Lim LS, Shen P, Gong YH, Lee LS, Yong EL. Dynamics of progestogenic activity in serum following administration of Ligusticum chuanxiong. Life Sci. 2006 Aug 22;79(13):1274-80